1. What UDvia-450 SR Tablets are and what they are used for?
UDvia-450 SR Tablets contain ursodeoxycholic acid, a naturally occurring bile acid.
It works by:
- Reducing cholesterol in bile
- Helping dissolve cholesterol gallstones
- Improving bile flow and reducing liver inflammation
UDvia-450 SR Tablets are used for:
- Dissolution of cholesterol gallstones
- Prevention of gallstone formation
- Treatment of chronic liver diseases such as:
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Cystic fibrosis–related liver disease
- Intrahepatic cholestasis (including in pregnancy)
2. What you need to know before you take UDvia-450 SR Tablets?
Do not take UDvia-450 SR Tablets if you:
- are allergic to ursodeoxycholic acid or any of the ingredients
- have acute inflammation of the gallbladder or bile ducts
- have blockage in the bile ducts
- have calcified gallstones
- have frequent biliary colic (severe gallstone pain)
- have non-functioning gallbladder
- have active stomach or duodenal ulcers
Warnings and precautions
Talk to your doctor before taking UDvia-450 SR Tablets if:
- you have liver problems
- you have gallstones
- you develop persistent diarrhea
- you are being treated for primary biliary cholangitis
Monitoring during treatment:
- Your doctor may regularly check liver function tests (LFTs)
- Ultrasound may be done to monitor gallstone dissolution
Special precautions
- Treatment should always be under medical supervision
- If diarrhea occurs, inform your doctor
- Women taking UDvia-450 SR for gallstones should use non-hormonal contraception
Children
- Can be used in children only if prescribed by a doctor
- Special care required in certain liver co Other medicines and UDvia-450 SR Tablets
Tell your doctor if you are taking:
- antacids containing aluminium
- cholesterol-lowering drugs (e.g., clofibrate)
- ciclosporin
- ciprofloxacin
- nitrendipine or statins
- These medicines may affect how UDvia-450 SR works or be affected by it.
UDvia-450 SR with food and drink
- Take with or after food as advised by your doctor
Pregnancy and breast-feeding
- If you are pregnant or planning pregnancy, consult your doctor before use
- Limited data available in pregnancy
- May be used only if clearly necessary
- Breastfeeding is generally considered safe, but consult your doctor
Driving and using machines
UDvia-450 SR has no or minimal effect on driving or operating machinery
3. How to take UDvia-450 SR Tablets?
Always take this medicine exactly as your doctor has told you.
Dosage depends on your condition and body weight
General guidelines:
- Gallstones: 8–10 mg/kg/day in divided doses
- Primary biliary cholangitis: 12–16 mg/kg/day
- Children (cystic fibrosis): 20–30 mg/kg/day
Your doctor will decide the exact dose.
How to take
- Swallow tablets whole with water
- Take regularly as prescribed
If you take more UDvia-450 SR than you should
- Overdose may cause diarrhea
- Contact your doctor immediately
If you forget a dose
- Do not take a double dose
- Take the next dose at the usual time
If you stop taking UDvia-450 SR
- Do not stop treatment without consulting your doctor
- Long-term treatment may be required
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects:
- Diarrhea
- Soft or pasty stools
Reporting side effects
If you get any side effects, talk to your doctor or pharmacist. You can also report side effects via email: medico@zorvia.com
How to store UDvia-450 SR Tablets
- Keep out of the sight and reach of children
- Store below 30°C
- Protect from light
- Do not use after the expiry date
5. Contents of the pack and other information
What UDvia-450 SR Tablets contain:
- Ursodeoxycholic acid 450mg
Other ingredients: As listed on the pack
What UDvia-450 SR Tablets look like and contents of the pack
- Available in strips of 10 tablets
Marketing Authorization Holder
Zorvia Healthcare Limited
Thane West, Maharashtra, India
This leaflet was issued on:
23rd March 2026
