1. What is Linectra-M 500/1000 and what is it used for
Linectra-M 500/1000 contains two medicines:
- Linagliptin – helps your body increase insulin release and reduce the amount of sugar in your blood
- Metformin – lowers blood sugar by reducing glucose production and improving insulin use
It is used in adults with type 2 diabetes mellitus to help control blood sugar levels along with diet and exercise.
2. What you need to know before you take Linectra-M 500/1000 tablet
Do NOT take this medicine if you:
- Have severe kidney problems
- Have diabetic ketoacidosis or metabolic acidosis
- Are allergic to linagliptin, metformin, or any ingredient in the tablet
Warnings and precautions
Talk to your doctor before taking this medicine if you:
- Have kidney, liver, or heart problems
- Drink alcohol frequently
- Are dehydrated (vomiting, diarrhoea, fever)
- Are scheduled for surgery or imaging tests with contrast dye
Important risks
Lactic acidosis (rare but serious)
Stop the medicine and seek medical help immediately if you have:
- Fast or difficult breathing
- Severe weakness or tiredness
- Muscle pain
- Stomach pain
- Feeling cold
Low blood sugar (Hypoglycaemia)
More likely if taken with insulin or other diabetes medicines. Symptoms include:
- Sweating
- Dizziness
- Hunger
- Fast heartbeat
Pancreatitis (inflammation of pancreas)
Stop the medicine and contact a doctor if you have:
- Severe stomach pain (may spread to the back)
- Vomiting
Allergic reactions
Seek immediate help if you have:
- Rash or itching
- Swelling of face, lips, or throat
- Difficulty breathing
Other medicines and Linectra-M
Tell your doctor if you are taking:
- Insulin or sulfonylureas (risk of low sugar)
- Diuretics, steroids, or thyroid medicines
- Certain antibiotics or heart medicines
- Alcohol (avoid excessive intake)
Pregnancy and breastfeeding
- Do not use during pregnancy
- Inform your doctor if you are pregnant or planning pregnancy
- Consult your doctor before breastfeeding
Driving and using machines
This medicine usually does not affect your ability to drive.
However, be careful if you experience low blood sugar.
3. How to take Linectra-M 500/1000 tablets?
- Take once daily with a meal
- Swallow the tablet whole
- Do NOT crush, chew, or break
- Follow your doctor’s instructions carefully
Missed dose
- Take it as soon as you remember
Do NOT take a double dose
4. Possible Side Effects
Common side effects
- Diarrhoea
- Nausea
- Stomach pain
- Taste changes
- Vitamin B12 deficiency
Less common side effects
- Cough
- Loss of appetite
- Skin rash or itching
Rare but serious
- Lactic acidosis
- Pancreatitis
- Severe allergic reactions
- Skin blistering (bullous pemphigoid)
Contact your doctor if you notice any unusual symptoms.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. You can also report side effects via email: medico@zorvia.com
Reporting side effects helps provide more information about the safety of this medicine.
5. How to store Linectra-M 500/1000 tablets?
Keep out of reach of children.
Store below 30°C in a dry place. Protect from light.
6. Contents of the pack and other information
What Linectra-M 500/1000 tablet contains:
The active ingredients are Linagliptin and Metformin Hydrochloride
Other ingredients:
Colours: Ferric Oxide USP-NF (Red) & Titanium Dioxide IP
What Linectra-M 500/1000 tablet looks like and contents of the pack
- Film coated tablet
- Pack size: As per carton
Marketing Authorization Holder
Zorvia Healthcare Limited
Suite 4, 10th Floor, Centaurus, Central Avenue,
Hiranandani Estate, Ghodbunder Road,
Thane West, Maharashtra, India—400607.
